Cerebral ornithine decarboxylase levels following gestational exposure to cocaine

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Cerebral ornithine decarboxylase levels following gestational exposure to cocaine.

The pre- and postnatal developmental course of cerebral ornithine decarboxylase (ODC) has been studied in infant rats after treatment of pregnant dams with cocaine. Levels of cocaine attained in brains and serum of embryos were not initially increased over corresponding maternal values, but were more persistent. However, cocaine was not longer detectable in these tissues 4 days after administra...

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Ornithine decarboxylase activity in L929 cells following exposure to 60 Hz magnetic fields.

To determine whether there is a biological basis for epidemiological studies which suggest an association between exposure to magnetic fields and cancer, we have attempted to replicate earlier findings on cellular enzymes related to cell proliferation. Here we report on an effort to replicate the doubling of ornithine decarboxylase (ODC) activity in L929 murine fibroblasts following exposure to...

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3417 Retinal vascular disruption associated with gestational exposure to cocaine

Puroose: The present study investigated whether flupirtine, a nonopioid analgesic agent with some NMDA antagonistic properties in viva and in vitro, protects from ischaemic retinal injury. Methods and Results: Retinal ischaemia was induced either by transient occlusion of both common carotid arteries in the rat or by a “suction cup procedure” which raises the intraocular pressure in the rabbit....

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Pregnancy outcome following gestational exposure to azithromycin

BACKGROUND Azithromycin is an azalide antibiotic with an extensive range of indications and has become a common treatment option due to its convenient dosing regimen and therapeutic advantages. Human studies addressing gestational use of azithromycin have primarily focused on antibiotic efficacy rather than fetal safety. Our primary objective was to evaluate the possibility of teratogenic risk ...

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Ornithine decarboxylase levels in patients with normal colonic mucosa.

We describe a systematic examination of ornithine decarboxylase activity in 120 colonic mucosal samples which were obtained from 20 subjects without colonic disease to establish the normal mean and standard deviation from proximal to distal colon. Ornithine decarboxylase activity was determined by releasing CO2 from DL-[1-14C]ornithine. The mean ornithine decarboxylase levels (CO2 liberated) ra...

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ژورنال

عنوان ژورنال: International Journal of Developmental Neuroscience

سال: 1990

ISSN: 0736-5748,1873-474X

DOI: 10.1016/0736-5748(90)90040-9